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eurysterols a and b, cytotoxic and antifungal steroidal sulfates from a marine sponge of the genus euryspongia.two new steroidal sulfates, eurysterols a (1) and b (2), were isolated from an undescribed marine sponge of the genus euryspongia collected in palau. the structures of the new compounds were assigned by nmr spectroscopic data interpretation. compounds 1 and 2 showed cytotoxicity against human colon carcinoma (hct-116) cells with ic50 values of 2.9 and 14.3 microg/ml, respectively, and exhibited antifungal activity against amphotericin b-resistant and wild-type strains of candida albicans with mi ...200717378608
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