imipenem resistance in aerobic gram-negative bacteria.a prospective study was undertaken to observe the emergence of resistance to imipenem, if any, among aerobic gram-negative bacteria. a total of 736 isolates were tested during 1994-95 and less than 1% of them were resistant to imipenem, whereas the next year ('95-'96) the rate increased to 11 of the 903 isolates tested. the resistant isolates during '94-'95 were all stenotrophomonas maltophilia whereas the spectrum of resistant bacterial species increased in '95-'96 to include pseudomonas aerugi ...19989603633
characterization of extended-spectrum beta-lactamase (esbl)-producing kuwait and uk strains identified by the vitek system, and subsequent comparison of the vitek system with other commercial esbl-testing systems using these strains.two hundred and fifty-one unique patient isolates of klebsiella pneumoniae (123), escherichia coli (114), klebsiella oxytoca (7), enterobacter cloacae (5) and citrobacter freundii (2), flagged as extended-spectrum beta-lactamase (esbl) positive by the vitek system (gns-526 card), were collected. these strains were isolated from a variety of clinical specimens submitted to the clinical bacteriology laboratories of the royal infirmary of edinburgh (rie), edinburgh, uk (and associated gp practices) ...200616533989
multiplex pcr for detection of plasmid-mediated quinolone resistance qnr genes in esbl-producing enterobacterial develop a rapid and reliable single-tube-based pcr technique for detecting simultaneously the plasmid-mediated quinolone resistance qnra, qnrb and qnrs genes.200717561500
emergence of new sequence type oxa-48 carbapenemase-producing enterobacteriaceae in kuwait.the aim of this study was to investigate the infections due to oxa-48 carbapenemase-producing bacteria in tertiary hospitals in kuwait (september 2011 to april 2013) and to determine the sequence types (sts) of the corresponding isolates. eleven oxa-48 carbapenemase-producing enterobacteriaceae isolates were recovered from patients treated in nine different hospitals in kuwait. susceptibility testing to eighteen antibiotics was done using the e-test. pcr assays were performed for the detection o ...201525551428
high prevalence of vim-4 and ndm-1 metallo-β-lactamase among carbapenem-resistant enterobacteriaceae.the purpose of this study was to identify the mechanisms leading to carbapenem resistance among multidrug-resistant enterobacteriaceae isolates recovered from hospitalized patients with nosocomial infections in mubarak al kabeer hospital, kuwait. fourteen carbapenem-resistant enterobacteriaceae isolates were obtained from inpatients in different wards and intensive care units between april 2009 and february 2011. antibiotic susceptibilities were determined using the e-test method. genes encoding ...201323639985
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