Publications

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multiplex pcr for detection of plasmid-mediated quinolone resistance qnr genes in esbl-producing enterobacterial isolates.to develop a rapid and reliable single-tube-based pcr technique for detecting simultaneously the plasmid-mediated quinolone resistance qnra, qnrb and qnrs genes.200717561500
characterization of extended-spectrum beta-lactamase (esbl)-producing kuwait and uk strains identified by the vitek system, and subsequent comparison of the vitek system with other commercial esbl-testing systems using these strains.two hundred and fifty-one unique patient isolates of klebsiella pneumoniae (123), escherichia coli (114), klebsiella oxytoca (7), enterobacter cloacae (5) and citrobacter freundii (2), flagged as extended-spectrum beta-lactamase (esbl) positive by the vitek system (gns-526 card), were collected. these strains were isolated from a variety of clinical specimens submitted to the clinical bacteriology laboratories of the royal infirmary of edinburgh (rie), edinburgh, uk (and associated gp practices) ...200616533989
multiyear, multinational survey of the incidence and global distribution of metallo-β-lactamase-producing enterobacteriaceae and pseudomonas aeruginosa.metallo-β-lactamases (mbls) hydrolyze all classes of β-lactams except monobactams and are not inhibited by classic serine β-lactamase inhibitors. gram-negative pathogens isolated from patient infections were collected from 202 medical centers in 40 countries as part of a global surveillance study from 2012 to 2014. carbapenem-nonsusceptible enterobacteriaceae and pseudomonas aeruginosa were characterized for bla genes encoding vim, imp, ndm, spm, and gim variants using pcr and sequencing. a tota ...201626643349
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