Publications

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multiplex pcr for detection of plasmid-mediated quinolone resistance qnr genes in esbl-producing enterobacterial isolates.to develop a rapid and reliable single-tube-based pcr technique for detecting simultaneously the plasmid-mediated quinolone resistance qnra, qnrb and qnrs genes.200717561500
multiyear, multinational survey of the incidence and global distribution of metallo-β-lactamase-producing enterobacteriaceae and pseudomonas aeruginosa.metallo-β-lactamases (mbls) hydrolyze all classes of β-lactams except monobactams and are not inhibited by classic serine β-lactamase inhibitors. gram-negative pathogens isolated from patient infections were collected from 202 medical centers in 40 countries as part of a global surveillance study from 2012 to 2014. carbapenem-nonsusceptible enterobacteriaceae and pseudomonas aeruginosa were characterized for bla genes encoding vim, imp, ndm, spm, and gim variants using pcr and sequencing. a tota ...201626643349
characterization of extended-spectrum beta-lactamase (esbl)-producing kuwait and uk strains identified by the vitek system, and subsequent comparison of the vitek system with other commercial esbl-testing systems using these strains.two hundred and fifty-one unique patient isolates of klebsiella pneumoniae (123), escherichia coli (114), klebsiella oxytoca (7), enterobacter cloacae (5) and citrobacter freundii (2), flagged as extended-spectrum beta-lactamase (esbl) positive by the vitek system (gns-526 card), were collected. these strains were isolated from a variety of clinical specimens submitted to the clinical bacteriology laboratories of the royal infirmary of edinburgh (rie), edinburgh, uk (and associated gp practices) ...200616533989
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