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geographic variations, cloning, and functional analyses of the venom acidic phospholipases a2 of crotalus viridis viridis.geographic venom samples of crotalus viridis viridis were obtained from south dakota, wyoming, colorado, oklahoma, texas, new mexico, and arizona. from these samples, the phospholipases a(2) (pla(2)s) were purified and their n-terminal sequences, precise masses, and in vitro enzymatic activities were determined. we purified two to four distinct acidic pla(2)s from each sample; some of them displayed different inhibition specificities toward mammalian platelets. one of the acidic pla(2)s induced ...200312623078
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