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outbreak of highly pathogenic avian influenza in japan and anti-influenza virus activity of povidone-iodine products.on january 12, 2004, an outbreak of highly pathogenic avian influenza, caused by the h5n1 strain, occurred in a one-layer flock in yamaguchi prefecture, japan. it had been 79 years since the last outbreak of avian influenza was confirmed in japan. by february, 3 additional outbreaks had occurred (1 in oita prefecture and 2 in kyoto prefecture). influenza viruses are enveloped viruses and are relatively sensitive to inactivation by lipid solvents, such as detergents. infectivity is also rapidly d ...200616490988
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