| detection of a novel hepatitis e-like virus in faeces of wild rats using a nested broad-spectrum rt-pcr. | hepatitis e is a rare human disease in developed countries. it is caused by hepatitis e virus (hev), which is probably transmitted zoonotically to humans from domestic pigs and wild boars. multiple reports on the detection of hev-specific antibodies in rats have suggested the presence of an hev-related agent; however, infectious virus or a viral genome has not been demonstrated so far. here, a nested broad-spectrum rt-pcr protocol was developed capable of detecting different hev types including ... | 2010 | 19889929 |
| rat hepatitis e virus: geographical clustering within germany and serological detection in wild norway rats (rattus norvegicus). | zoonotic hepatitis e virus (hev) infection in industrialised countries is thought to be caused by transmission from wild boar, domestic pig and deer as reservoir hosts. the detection of hev-specific antibodies in rats and other rodents has suggested that these animals may represent an additional source for hev transmission to human. recently, a novel hev (rathev) was detected in norway rats from hamburg, germany, showing the typical genome organisation but a high nucleotide and amino acid sequen ... | 2012 | 22554648 |