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the hla-dqb alleles and amino acid variants of the vitamin d-binding protein in diabetic patients in alsace.the hla-dqb1 chain, in particular the amino acid in position 57, and genetic variants of the vitamin d-binding protein (dbp) have been reported to be associated with type 1 diabetes. there are two known polymorphisms in exon 11 of the dbp gene resulting in amino acid variants: codons 416 gat --> gag (asp --> glu) and 420 acg --> aag (thr --> lys). we compared distribution of dqb1 alleles and amino acid variants of dbp in type 1 diabetic patients (n = 44) in the alsacian population and in healthy ...200111239517
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