effects of agricultural pesticides on the immune system of xenopus laevis and rana pipiens.over the last 30 years, there have been mass declines in diverse geographic locations among amphibian populations. multiple causes have been suggested to explain this decline. among these, environmental pollution is gaining attention. indeed, some chemicals of environmental concern are known to alter the immune system. given that amphibians are frequently exposed to agricultural pesticides, it is possible that these pollutants alter their immune system and render them more susceptible to differe ...200415019249
the k-cl cotransporter kcc3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum.peripheral neuropathy associated with agenesis of the corpus callosum (accpn) is a severe sensorimotor neuropathy associated with mental retardation, dysmorphic features and complete or partial agenesis of the corpus callosum. accpn is transmitted in an autosomal recessive fashion and is found at a high frequency in the province of quebec, canada. accpn has been previously mapped to chromosome 15q. the gene slc12a6 (solute carrier family 12, member 6), which encodes the k+-cl- transporter kcc3 a ...200212368912
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