| dna damage in peripheral blood lymphocytes and association with polymorphisms in the promoter region of the cyp2e1 gene in alcoholics from central brazil. | dna damage caused by the accumulation of bio-products generated in the biotransformation of ethanol to acetaldehyde mediated by the cyp2e1 enzyme has been studied. to evaluate dna damage in peripheral blood lymphocytes and the possible association with polymorphisms in the promoter region of the cyp2e1 gene, we performed a case-control study including 75 alcoholics and 59 individuals who consume alcohol socially. alcoholics were previously diagnosed by the psychosocial care center - alcohol and ... | 2016 | 27916141 |