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lifetime pcb 153 bioaccumulation and pharmacokinetics in pilot whales: bayesian population pbpk modeling and markov chain monte carlo simulations.physiologically based pharmacokinetic (pbpk) models for wild animal populations such as marine mammals typically have a high degree of model uncertainty and variability due to the scarcity of information and the embryonic nature of this field. parameters values used in marine mammals models are usually taken from other mammalian species (e.g. rats or mice) and might not be entirely suitable to properly explain the kinetics of pollutants in marine mammals. therefore, several parameters for a pbpk ...201424080004
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