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parallel microtubules and other conserved elements of dorsal axial specification in the direct developing frog, eleutherodactylus coqui.specification of the dorsal axis in commonly studied frogs, such as xenopus laevis and rana pipiens, depends on a microtubule-mediated movement of cytoplasm in the fertilized egg. the puerto rican tree frog, eleutherodactylus coqui, has an egg that is twenty times the volume of that of x. laevis, raising the question as to whether the mechanism of dorsal axial specification is conserved in these large eggs. fertilized eggs of e. coqui develop a transient array of parallel microtubules, similar t ...200312590350
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