Publications

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strategies to mitigate a mycobacterium marinum outbreak in a zebrafish research facility.in 2011, the zebrafish research facility at the university of oregon experienced an outbreak of mycobacterium marinum that affected both research fish and facility staff. a thorough review of risks to personnel, the zebrafish veterinary care program, and zebrafish husbandry procedures at the research facility followed. in the years since 2011, changes have been implemented throughout the research facility to protect the personnel, the fish colony, and ultimately the continued success of the zebr ...201627351618
facility design and health management program at the sinnhuber aquatic research laboratory.the number of researchers and institutions moving to the utilization of zebrafish for biomedical research continues to increase because of the recognized advantages of this model. numerous factors should be considered before building a new or retooling an existing facility. design decisions will directly impact the management and maintenance costs. we and others have advocated for more rigorous approaches to zebrafish health management to support and protect an increasingly diverse portfolio of ...201626981844
using passive sampling and zebrafish to identify developmental toxicants in complex mixtures.using effects-directed analysis, we investigated associations previously observed between polycyclic aromatic hydrocarbons (pahs) and embryotoxicity in field-deployed low-density polyethylene (ldpe). we conducted effects-directed analysis using a zebrafish embryo assay and iterative fractionation of extracts of ldpe that were deployed in the portland harbor superfund megasite, oregon (usa). whole extracts induced toxicity including mortality, edema, and notochord distortion at 20% effect concent ...201728326615
a virtual tour of the guide for zebrafish users.phs-funded and aaalac-accredited facilities are required to use the guide as the basis for setting up a zebrafish care and use program. the authors describe how they accomplished this task at the university of oregon zebrafish facility.200211923859
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