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effects of il-10 on systemic inflammatory responses during sublethal primate endotoxemia.il-10 protects mice from lps-induced lethality. to determine the effects of il-10 on lps-induced inflammatory responses, six papio anubis baboons were i.v. injected with a sublethal dose of lps (salmonella typhimurium; 500 microg/kg) directly preceded by either human ril-10 (n = 3, 500 microg/kg) or diluent (n = 3). il-10 strongly inhibited lps-induced release of tnf, il-6, il-8, and il-12 (all p < 0.05). by contrast, il-10 did neither influence the activation of the coagulation system (plasma l ...19979029140
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