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study of live typhoid vaccine in chimpanzees.streptomycin-dependent salmonella typhi containing o and h antigens was administered as a live oral antityphoid vaccine to chimpanzees. five animals served as controls; 5 others received the vaccine 4 times at 3-day intervals; 4 further animals were given 4 doses of vaccine at 3-day intervals together with streptomycin; and 1 animal received the 4 doses of vaccine and a daily dose of streptomycin. the individual vaccine doses varied between 36x10(9) and 82x10(9) organisms, totalling about 258x10 ...19704194259
studies on infection and immunity in experimental typhoid fever. 8. intravenous and intra-lymph node challenge of chimpanzees with salmonella typhi. 19684880691
studies on infection and immunity in experimental typhoid fever. vii. the distribution of salmonella typhi in chimpanzee tissue following oral challenge, and the relationship between the numbers of bacilli and morphologic lesions. 19685668032
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