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serological response of non-human primates to human melanoma disialoganglioside gd3.the immunogenicity of the disialoganglioside, gd3, a melanoma-tumor-associated antigen, has been evaluated in non-human primates. sera from four chimpanzees and two monkeys were evaluated for anti-gd3 antibody activity by solid-phase radioimmunoassay using gd3 and control gangliosides as targets. serum from one monkey, immunized with cells from a melanoma cell line, was strongly reactive with gd3, having a titer of greater than 2500. in contrast, serum from this animal was non-reactive with seve ...19892731185
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