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selection of the chimpanzee over the baboon as a model for helicobacter pylori infection.baboons (papio sp.) and chimpanzees (pan troglodytes) were screened for the presence of helicobacter pylori. the gastric mucosae of the baboons were colonized by large spiral bacteria. however, a group of adult chimpanzees were identified that were free of spiral gastric bacteria, with five animals being recruited into an h. pylori challenge study. these animals were inoculated orogastrically with one of four strains of h. pylori and followed for up to 26 weeks. h. pylori was established in one ...19921499934
stat3-induced wnt5a signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (review).leukemia inhibitory factor (lif), oncostatin m, leptin, ciliary neurotrophic factor, cardiotrophin 1, cardiotrophin-like cytokine factor 1, interleukin 6 (il6), interleukin 11 and interleukin 27 activate the gp130-jak-stat3 signaling cascade. here, wnt5a was characterized as the evolutionarily conserved target of the stat3 signaling cascade based on 11-bp-spaced tandem stat3-binding sites within intron 4 of human, chimpanzee, cow, mouse and rat wnt5a orthologs. canonical wnt5a signaling through ...200717203201
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