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two bacterial infection models in tree shrew for evaluating the efficacy of antimicrobial agents.animal models are essential for the development of new anti-infectious drugs. although some bacterial infection models have been established in rodents, small primate models are rare. here, we report on two bacterial infection models established in tree shrew (tupaia belangeri chinensis). a burnt skin infection model was induced by dropping 5×10(6) cfu of staphylococcus aureus on the surface of a wound after a third degree burn. this dose of s. aureus caused persistent infection for 7 days and o ...201222345001
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