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specificity of avian leukosis virus-induced hyperlipidemia.rous-associated virus 7 (rav-7) is a subgroup c avian leukosis virus which does not transform cells in vitro or carry an oncogene. when injected into 1-day-old hatched chicks, rav-7 causes a low incidence of lymphoid leukosis after a latent period of several months. in contrast, infection of 10-day-old chicken embryos with rav-7 leads to a disease syndrome characterized by stunting, obesity, atrophy of the bursa and the thymus, high triglyceride and cholesterol levels, reduced thyroxine levels, ...19846323732
genetic determinants of neoplastic diseases induced by a subgroup f avian leukosis virus.two subgroup f avian leukosis viruses, ring-necked pheasant virus (rpv) and rav-61, were previously shown to induce a high incidence of a fatal proliferative disorder in the lungs of infected chickens. these lung lesions, termed angiosarcomas, appear rapidly (4 to 5 weeks after infection), show no evidence of proto-oncogene activation by proviral integration, and are not induced by avian leukosis viruses belonging to other subgroups. to identify the viral sequences responsible for induction of t ...19873029416
rapid induction of b-cell lymphomas: insertional activation of c-myb by avian leukosis virus.eu-8 is a recombinant avian leukosis virus (alv) constructed in vitro, which carries long terminal repeats and gag and pol genes from ring-necked pheasant virus and the env gene from ur2av. unlike either parent virus, when injected into 10-day-old chicken embryos, eu-8 induces a high incidence of clonally arising b-cell lymphomas within an unusually short latent period, often causing death within 5 to 7 weeks after infection. these tumors differ from the classic lymphoid leukosis induced by alv ...19882831403
avian leukosis viruses of different subgroups and types isolated after passage of rous sarcoma virus-rous-associated virus-0 in cells from different ring-necked pheasant embryos.avian leukosis viruses of subgroups a and f (rav-a and rav-f) arose at a low rate after passage of rous sarcoma virus-rous-associated virus-0, which is subgroup e, in cells from ring-necked pheasant embryos. in cells of two embryos, all of the viruses isolated after virus passage were rav-f. however, in cells of a third embryo, both rav-a and rav-f were isolated. in addition, there sometimes were type-specific differences among the different isolates of rav-a and rav-f from the cells of single e ...1976183006
induction of angiosarcomas by ring-necked pheasant virus.ring-necked pheasant virus, an avian leukosis virus, when injected into 10-day old chick embryos, caused angiosarcomas in the lungs of infected chickens within a short time. angiosarcomas appeared as localized foci of proliferating cells in the lungs as early as 2 weeks posthatch, and by 6 weeks, the lungs of the infected chickens were frequently filled with tumor cells. between 3 and 10 weeks of age, 80% of infected chickens died of the angiosarcomas; the 20% which lived 8 weeks or longer had s ...19836299960
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