Publications

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lack of evidence for infection with simian immunodeficiency virus in bonobos. 200211839156
old world monkeys and new age science: the evolution of nonhuman primate systems virology.nonhuman primate (nhp) biomedical models are critical to our understanding of human health and disease, yet we are still in the early stages of developing sufficient tools to support primate genomic research that allow us to better understand the basis of phenotypic traits in nhp models of disease. a mere 7 years ago, the limited nhp transcriptome profiling that was being performed was done using complementary dna arrays based on human genome sequences, and the lack of nhp genomic information an ...201324174440
eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir.chimpanzees in west central africa (pan troglodytes troglodytes) are endemically infected with simian immunodeficiency viruses (sivcpzptt) that have crossed the species barrier to humans and gorillas on at least five occasions, generating pandemic and nonpandemic forms of human immunodeficiency virus type 1 (hiv-1) as well as gorilla siv (sivgor). chimpanzees in east africa (pan troglodytes schweinfurthii) are also infected with sivcpz; however, their viruses (sivcpzpts) have never been found in ...201222837215
the role of the antiviral apobec3 gene family in protecting chimpanzees against lentiviruses from monkeys.cross-species transmissions of viruses from animals to humans are at the origin of major human pathogenic viruses. while the role of ecological and epidemiological factors in the emergence of new pathogens is well documented, the importance of host factors is often unknown. chimpanzees are the closest relatives of humans and the animal reservoir at the origin of the human aids pandemic. however, despite being regularly exposed to monkey lentiviruses through hunting, chimpanzees are naturally inf ...201526394054
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