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alterations in the course of experimental syphilis associated with concurrent simian immunodeficiency virus infection.case reports suggest that the course of syphilis is altered in patients infected with human immunodeficiency virus (hiv). to investigate this issue, a model of syphilis in rhesus macaques with and without simian immunodeficiency virus (siv) was developed. after intradermal inoculation with treponema pallidum, 2 siv-infected monkeys had persistent ulcerative primary lesions and 1 developed secondary syphilis. two siv-uninfected controls developed transient nonulcerative primary lesions. only the ...19921583318
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