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fetal brain lesions after subcutaneous inoculation of zika virus in a pregnant nonhuman primate.we describe the development of fetal brain lesions after zika virus (zikv) inoculation in a pregnant pigtail macaque. periventricular lesions developed within 10 d and evolved asymmetrically in the occipital-parietal lobes. fetal autopsy revealed zikv in the brain and significant cerebral white matter hypoplasia, periventricular white matter gliosis, and axonal and ependymal injury. our observation of zikv-associated fetal brain lesions in a nonhuman primate provides a model for therapeutic eval ...201627618651
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