| identification and characterization of a phospholipase a2 from the venom of the saw-scaled viper: novel bactericidal and membrane damaging activities. | phospholipase a(2) (pla(2)), a common toxic component of snake venom, has been implicated in various pharmacological effects. in this study, a basic myotoxic pla(2), named ectx-i was isolated from echis carinatus snake venom by using gel filtration on superdex g-75, and reverse phase hplc on c18 and c8 sepharose columns. pla(2), ectx-i was 13,861.72 molecular weight as estimated by maldi-tof (15 kd by sds-page), and consisted of 121 amino acid residues cross-linked by seven disulfide bonds. the ... | 2010 | 20723574 |
| assessment of cultivable oral bacterial flora from important venomous snakes of india and their antibiotic susceptibilities. | snakebite is a common, frequently devastating, occupational, socio-economic hazard, and it has a great impact on the rural population of india. snakebite is a major cause of the human morbidity and mortality since ancient times, as it not only affects the victim by systemic envenomation but also by wound infections originating from deadly pathogenic microorganisms from the oral cavity of the offending snake. the pathogens from the oral cavity of the snake tend to initiate an infection, resulting ... | 2017 | 28733908 |