demonstration of helicobacter pylori-like organisms in the gastric mucosa of captive exotic carnivores.samples of gastric tissue from the cardiac, fundic and pyloric region of 30 carnivores comprising 12 tigers (panthera tigris), 10 lions (panthera leo), three pumas (felis concolor), two leopards (panthera pardus), one serval (felis serval), one wolf (canis lupus) and one hyena (crocuta crocuta) kept at german zoological gardens were subjected to histopathological and immunohistochemical examination. selected tissue specimens of 12 animals were examined also by electron microscopy. the purpose of ...19979076597
chronic gastritis in tigers associated with helicobacter acinonyx.helicobacter pylori-like organisms (hplos) were isolated from the gastric mucosa of two sumatran tigers and identified by polymerase chain reaction analysis as helicobacter acinonyx. at histological examination, both tigers revealed a chronic gastritis associated with hplos as demonstrated by immunolabelling and electron microscopy. this is the first isolation of h. acinonyx from tigers, in which, as previously reported in cheetahs, it may be a cause of gastritis.19989717128
who ate whom? adaptive helicobacter genomic changes that accompanied a host jump from early humans to large felines.helicobacter pylori infection of humans is so old that its population genetic structure reflects that of ancient human migrations. a closely related species, helicobacter acinonychis, is specific for large felines, including cheetahs, lions, and tigers, whereas hosts more closely related to humans harbor more distantly related helicobacter species. this observation suggests a jump between host species. but who ate whom and when did it happen? in order to resolve this question, we determined the ...200616789826
helicobacter acinonychis: genetic and rodent infection studies of a helicobacter pylori-like gastric pathogen of cheetahs and other big cats.insights into bacterium-host interactions and genome evolution can emerge from comparisons among related species. here we studied helicobacter acinonychis (formerly h. acinonyx), a species closely related to the human gastric pathogen helicobacter pylori. two groups of strains were identified by randomly amplified polymorphic dna fingerprinting and gene sequencing: one group from six cheetahs in a u.s. zoo and two lions in a european circus, and the other group from a tiger and a lion-tiger hybr ...200414702304
gastric and enterohepatic helicobacters other than helicobacter pylori.during the past year, research on non-helicobacter pylori species has intensified. h. valdiviensis was isolated from wild birds, and putative novel species have been isolated from bengal tigers and australian marsupials. various genomes have been sequenced: h. bilis, h. canis, h. macacae, h. fennelliae, h. cetorum, and h. suis. several studies highlighted the virulence of non-h. pylori species including h. cinaedi in humans and hyperlipidemic mice or h. macacae in geriatric rhesus monkeys with i ...201425167947
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