Publications

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immune response to and histopathology of campylobacter jejuni infection in ferrets (mustela putorius furo).campylobacter jejuni is 1 of the most common enteric bacterial pathogens worldwide. the mechanisms of pathogenesis remain obscure, in part because of limitations of small animal models. young ferrets develop diarrhea when fed c. jejuni, but their pathology and the immune response after infection have not been examined in detail. in the present study, we examined the pathogenesis of c. jejuni cg8421 and associated immune responses in ferrets. after oral infection with c. jejuni cg8421, 86.7% of t ...200919712577
proliferative colitis in ferrets.during a 4-month period, 31 of 156 ferrets (mustela putorius) in a biomedical research program developed protracted diarrhea. clinical signs were green mucohemorrhagic fecal material, partially prolapsed rectum, anorexia, body weight loss, and dehydration. nine of the affected animals were necropsied. on gross examination, the descending colon was grossly thick and histologically characterized by marked proliferation of the mucosa, relatively few goblet cells, mixed inflammatory cell infiltrate, ...19827091850
campylobacter jejuni infection in the ferret: an animal model of human campylobacteriosis.campylobacter infection in weanling ferrets (mustela putorius furo) was studied as an animal model for enteric campylobacteriosis in persons. the screening of fecal cultures on selective campylobacter media showed that campylobacter jejuni/coli was not present in the normal enteric flora. intragastric feeding of a mixture of cat feed and 2.5 x 10(8) c jejuni isolated from ferrets with naturally occurring proliferative colitis was accomplished. all ferrets (n = 8) became infected on 3 days after ...19873826848
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