Publications

TitleAbstractYear
Filter
PMID
Filter
biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah.an epizootic of feline infectious peritonitis in a captive cheetah population during 1982-1983 served to focus attention on the susceptibility of the cheetah (acinoyx jubatus) to infectious disease. subsequent observations based upon seroepidemiological surveys and electron microscopy of fecal material verified that cheetahs were indeed capable of being infected by coronaviruses, which were antigenically related to coronaviruses affecting domestic cats, i.e. feline infectious peritonitis virus/f ...19882849387
detection of feline coronavirus infection in captive cheetahs (acinonyx jubatus) by polymerase chain reaction.feline coronavirus genetic elements were detected by polymerase chain reaction from blood, fecal samples, and effusive fluid collected from 33 cheetahs in the u.s.a. feline coronavirus-specific serum antibodies were also measured by indirect immunofluorescence. ten cheetahs were positive for viral shedding by polymerase chain reaction, whereas 13 were seropositive by immunofluorescence. results of serology did not consistently correlate with shedding of virus, and the capture antigen used for de ...200112790391
detection of feline coronavirus infection in southern african nondomestic felids.feline coronavirus (fcov) infects members of the felidae family with results ranging from seroconversion with no disease to fatal feline infectious peritonitis (fip). infection of non-domestic felids with fcov is of concern, particularly in endangered populations such as cheetahs (acinonyx jubatus). in this investigation, we tested 342 animals in the republic of south africa and namibia, including 140 animals from wild populations, for evidence of fcov infection by serology and/or reverse transc ...200314567213
serosurvey of viral infections in free-ranging namibian cheetahs (acinonyx jubatus).cheetahs (acinonyx jubatus) in captivity have unusually high morbidity and mortality from infectious diseases, a trait that could be an outcome of population homogeneity or the immunomodulating effects of chronic stress. free-ranging namibian cheetahs share ancestry with captive cheetahs, but their susceptibility to infectious diseases has not been investigated. the largest remaining population of free-ranging cheetahs resides on namibian farmlands, where they share habitat with domestic dogs an ...200415137485
seroprevalences to viral pathogens in free-ranging and captive cheetahs (acinonyx jubatus) on namibian farmland.cheetah populations are diminishing rapidly in their natural habitat. one reason for their decline is thought to be a high susceptibility to (infectious) diseases because cheetahs in zoos suffer from high disease-induced mortality. data on the health status of free-ranging cheetahs are scarce, and little is known about their exposure and susceptibility to infectious diseases. we determined seroprevalences to nine key viruses (feline herpesvirus 1, feline calicivirus, feline parvovirus, feline co ...201019955325
prevalence and implications of feline coronavirus infections of captive and free-ranging cheetahs (acinonyx jubatus).the extent and progression of exposure to feline infectious peritonitis (fip) virus in the cheetah, acinonyx jubatus, was monitored by a world-wide serological survey with indirect fluorescent antibody titers to coronavirus. the indirect fluorescent antibody assay was validated by western blots, which showed that all indirect fluorescent antibody-positive cheetah sera detected both domestic cat and cheetah coronavirus structural proteins. there was a poor correlation between indirect fluorescent ...19902157864
plagues and adaptation: lessons from the felidae models for sars and aids.research studies of infectious disease outbreaks in wild species of the cat family felidae have revealed unusual details regarding forces that shape population survival and genetic resistance in these species. a highly virulent feline coronavirus epidemic in african cheetahs, a disease model for human sars, illustrates the critical role of ancestral population genetic variation. widespread prevalence of species specific feline immunodeficiency virus (fiv), a relative of hiv-aids, occurs with lit ...200632226081
detection of feline coronavirus in cheetah (acinonyx jubatus) feces by reverse transcription-nested polymerase chain reaction in cheetahs with variable frequency of viral shedding.cheetahs (acinonyx jubatus) are a highly threatened species because of habitat loss, human conflict, and high prevalence of disease in captivity. an epidemic of feline infectious peritonitis and concern for spread of infectious disease resulted in decreased movement of cheetahs between u.s. zoological facilities for managed captive breeding. identifying the true feline coronavirus (fcov) infection status of cheetahs is challenging because of inconsistent correlation between seropositivity and fe ...201223272344
analysis of genetic mutations in the 7a7b open reading frame of coronavirus of cheetahs (acinonyx jubatus).to analyze the 7a7b genes of the feline coronavirus (fcov) of cheetahs, which are believed to play a role in virulence of this virus.200616579755
lack of antibodies to coronaviruses in a captive cheetah (acinonyx jubatus) population.cheetahs (acinonyx jubatus) (n = 40) were tested by means of an immunofluorescent test (ift) for the presence of antibodies to the feline coronavirus group. all cheetahs tested negatively and this was further confirmed by virus serum neutralisation.19911663166
comparative features of a coronavirus isolated from a cheetah with feline infectious peritonitis.a coronavirus which was isolated from a cheetah (acinonyx jubatus) that succumbed to feline infectious peritonitis was characterized in vitro. the virus was determined to be highly cell-associated with crandell feline kidney (crfk) cells and was routinely maintained as a persistent infection (crfk 83-4497). the cheetah coronavirus was compared with other members of the feline coronavirus group including the feline enteric coronavirus (fecv) 79-1683 and the feline infectious peritonitis viruses ( ...19892546331
Displaying items 1 - 11 of 11