ciclopiroxolamine cream 1%: in vitro and in vivo penetration into the stratum corneum.studies were conducted to assess the penetration of 1% ciclopiroxolamine cream, establishing the concentrations of the antimycotic compound in different layers of the stratum corneum with two skin models. results of in vitro studies using skin from domestic pigs indicate that ciclopiroxolamine has the ability to penetrate fast into the epidermis, by inhibiting and killing inoculated trichophyton mentagrophytes. in vivo investigation of the stratum corneum has been performed in healthy human volu ...19911878248
ciclopirox olamine lotion 1%: bioequivalence to ciclopirox olamine cream 1% and clinical efficacy in tinea pedis.studies were conducted to assess the bioequivalence of a new antimycotic formulation, ciclopirox olamine lotion 1%, to an established compound, ciclopirox olamine cream 1%. results of in vitro studies, using skin samples from human cadavers and domestic pigs, demonstrated that the two formulations equally penetrate all layers of the stratum corneum and inhibit the growth of trichophyton mentagrophytes and candida albicans. in vivo studies in guinea pigs and in human volunteers demonstrated the c ...19892663159
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