| reston ebolavirus in humans and animals in the philippines: a review. | the 2008 reston ebolavirus infection event in domestic pigs has triggered continuing epidemiologic investigations among philippine health and veterinary agencies in collaboration with international filovirus experts. prior to this, there were only 3 known and documented reston ebolavirus outbreaks in nonhuman primates in the world, all traced back to a single geographic source in the philippines in a monkey breeding/export facility. the first one in 1989 was the first-ever ebola virus that emerg ... | 2011 | 21987747 |
| current perspectives on the phylogeny of filoviridae. | sporadic fatal outbreaks of disease in humans and non-human primates caused by ebola or marburg viruses have driven research into the characterization of these viruses with the hopes of identifying host tropisms and potential reservoirs. such an understanding of the relatedness of newly discovered filoviruses may help to predict risk factors for outbreaks of hemorrhagic disease in humans and/or non-human primates. recent discoveries such as three distinct genotypes of reston ebolavirus, unexpect ... | 2011 | 21742058 |
| discovery of swine as a host for the reston ebolavirus. | since the discovery of the marburg and ebola species of filovirus, seemingly random, sporadic fatal outbreaks of disease in humans and nonhuman primates have given impetus to identification of host tropisms and potential reservoirs. domestic swine in the philippines, experiencing unusually severe outbreaks of porcine reproductive and respiratory disease syndrome, have now been discovered to host reston ebolavirus (rebov). although rebov is the only member of filoviridae that has not been associa ... | 2009 | 19590002 |
| assessment of rodents as animal models for reston ebolavirus. | the emergence of reston ebolavirus (rebov) in domestic swine in the philippines has caused a renewed interest in rebov pathogenicity. here, the use of different rodent species as animal disease models for rebov was investigated. balb/c and stat1(-)(/-) mice, hartley guinea pigs, and syrian hamsters were inoculated intraperitoneally with rebov strain pennsylvania or reston08-a. although virus replication occurred in guinea pigs, hamsters, and stat1(-/-) mice, progression to disease was only obser ... | 2011 | 21987777 |
| molecular evidence of ebola reston virus infection in philippine bats. | in 2008-09, evidence of reston ebolavirus (restv) infection was found in domestic pigs and pig workers in the philippines. with species of bats having been shown to be the cryptic reservoir of filoviruses elsewhere, the philippine government, in conjunction with the food and agriculture organization of the united nations, assembled a multi-disciplinary and multi-institutional team to investigate philippine bats as the possible reservoir of restv. | 2015 | 26184657 |