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discovery of a highly divergent hepadnavirus in shrews from china.limited sampling means that relatively little is known about the diversity and evolutionary history of mammalian members of the hepadnaviridae (genus orthohepadnavirus). an important case in point are shrews, the fourth largest group of mammals, but for which there is limited knowledge on the role they play in viral evolution and emergence. here, we report the discovery of a novel shrew hepadnavirus. the newly discovered virus, denoted shrew hepatitis b virus (shbv), is divergent to be considere ...201930884426
host biology and anthropogenic factors affect hepadnavirus infection in a neotropical bat.the tent-making bat hepatitis b virus (tbhbv) is a hepadnavirus closely related to human hepatitis b virus. the ecology of tbhbv is unclear. we show that it is widespread and highly diversified in peters' tent-making bats (uroderma bilobatum) within panama, while local prevalence varied significantly between sample sites, ranging from 0 to 14.3%. females showed significantly higher prevalence than males, and pregnant females were more often acutely infected than non-reproductive ones. the distri ...201930564998
analysis of codon usage of horseshoe bat hepatitis b virus and its host.in the present analysis, codon usage strategies and base distribution of horseshoe bat hepatitis b virus (hbhbv) were analyzed and compared with its host rhinolophus sinicus, as no work was yet reported. the magnitude of synonymous codon usage bias (cub) in the virus and its host was low with higher proportion of the base c. notably, 21 more frequently used codons, 19 less frequently used codons and 3 underrepresented codons (tcg, acg and gcg) were found to be similar in both virus and its host ...202134171764
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