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rna interference targets arbovirus replication in culicoides cells.arboviruses are transmitted to vertebrate hosts by biting arthropod vectors such as mosquitoes, ticks, and midges. these viruses replicate in both arthropods and vertebrates and are thus exposed to different antiviral responses in these organisms. rna interference (rnai) is a sequence-specific rna degradation mechanism that has been shown to play a major role in the antiviral response against arboviruses in mosquitoes. culicoides midges are important vectors of arboviruses, known to transmit pat ...201223269795
measurement of the infection and dissemination of bluetongue virus in culicoides biting midges using a semi-quantitative rt-pcr assay and isolation of infectious virus.culicoides biting midges (diptera: ceratopogonidae) are the biological vectors of globally significant arboviruses of livestock including bluetongue virus (btv), african horse sickness virus (ahsv) and the recently emerging schmallenberg virus (sbv). from 2006-2009 outbreaks of btv in northern europe inflicted major disruption and economic losses to farmers and several attempts were made to implicate palaearctic culicoides species as vectors. results from these studies were difficult to interpre ...201323940643
culicoides sonorensis (diptera: ceratopogonidae) is not a competent vector of cache valley virus (family bunyaviridae, genus orthobunyavirus).we investigated the susceptibility of culicoides sonorensis to cache valley virus (cvv) (family bunyaviridae, genus orthobunyavirus) infection and the potential that it could be a vector or site of virus reassortment. cvv is native to the new world and causes disease in livestock. infected blood meals were fed to both a competent vector, anopheles quadrimaculatus, and culicoides sonorensis. all anopheles mosquitoes were infected as expected, but only 21 % of the c. sonorensis insects were suscep ...201323636406
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