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chimeric tick-borne encephalitis/dengue virus is attenuated in ixodes scapularis ticks and aedes aegypti mosquitoes.abstract in an effort to derive an efficacious live attenuated vaccine against tick-borne encephalitis, we generated a chimeric virus bearing the structural protein genes of a far eastern subtype of tick-borne encephalitis virus (tbev) on the genetic background of recombinant dengue 4 (den4) virus. introduction of attenuating mutations into the tbev envelope protein gene, as well as the den4 ns5 protein gene and 3' noncoding region in the chimeric genome, results in decreased neurovirulence and ...201021142950
[epidemiologic situation on dangerous infectious diseases on the territory of republic of abkhazia].data from literature and results of epizootological examination of the territory of republic of abkhazia in 2011 and 2012 that confirm the presence in the republic of natural foci of hemorrhagic fever with renal syndrome, west nile fever, crimean hemorrhagic fever, tick-borne encephalitis, q fever, tahyna, inkoo, bhanja, sindbis fever, anaplasmosis, tick-borne borreliosis, tularemia and leptospirosis are presented. rabies and anthrax are actual for abkhazia. spread of aedes aegypti mosquitos in ...201424605653
imported cases of dengue in poland and their diagnosis.infections with dengue virus are transmitted by mosquitoes. in tropical areas, it is mainly spread by aedes aegypti while in countries with lower temperatures by aedes albopictus. since 2010, autochthonous cases of dengue are also reported in europe. there are 4 serotypes of dengue virus (denv). no correlation between clinical presentation of disease and virus type, however, were determined. nevertheless, reinfection with different type of denv may lead to a serious, life-threatening condition. ...201425848785
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