Publications

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fatal cetacean morbillivirus infection in an australian offshore bottlenose dolphin (tursiops truncatus).a juvenile offshore bottlenose dolphin (tursiops truncatus) was found stranded with neurological signs and unable to swim or float unassisted. it subsequently died, succumbing to a combination of severe pneumonia and encephalitis. morbillivirus serum neutralisation test serology was positive (titre 1:16) for cetacean morbillivirus and negative for both phocine distemper virus and canine distemper virus. there was concurrent thymic and lymph node lymphoid depletion and necrosis, together with int ...201122008125
morbillivirus infection in live stranded, injured, trapped, and captive cetaceans in southeastern queensland and northern new south wales, australia.we report serologic evidence of cetacean morbillivirus (cmv) infection in five of eight cetacean species found live stranded, injured, or trapped along the coast of southeastern queensland and northern new south wales, australia between december 2005 and january 2011. antibody to cmv was detected in 13 of 27 (48%) wild cetaceans sampled. antibody prevalence was significantly higher in clinically diseased (69%) compared to nondiseased (18%) animals (p=0.018). there was high antibody prevalence (8 ...201222247373
clinicoimmunopathologic findings in atlantic bottlenose dolphins tursiops truncatus with positive cetacean morbillivirus antibody titers.sera from free-ranging atlantic bottlenose dolphins tursiops truncatus inhabiting the indian river lagoon (irl), florida were tested for antibodies to cetacean morbilliviruses from 2003 to 2007 as part of a multidisciplinary study of individual and population health. a suite of clinicoimmunopathologic variables were evaluated in morbillivirus-seropositive dolphins (n = 14) and seronegative healthy dolphins (n = 49). several important differences were found. serum alkaline phosphatase, creatine p ...201122303627
coinfection by cetacean morbillivirus and aspergillus fumigatus in a juvenile bottlenose dolphin (tursiops truncatus) in the gulf of mexico.a recently deceased juvenile male bottlenose dolphin (tursiops truncatus) was found floating in the gulf of mexico, off sand key in clearwater, florida. at autopsy, we identified pneumonia and a focus of malacia in the right cerebrum. cytologic evaluation of tissue imprints from the right cerebrum revealed fungal hyphae. fungal cultures of the lung and brain yielded aspergillus fumigatus, which was confirmed by amplification of a portion of the fungal nuclear ribosomal internal transcribed space ...201627698174
diagnosis of cetacean morbillivirus: a sensitive one step real time rt fast-pcr method based on sybr(®) green.cetacean morbillivirus (cemv) (family paramyxoviridae, genus morbillivirus) is considered the most pathogenic virus of cetaceans. it was first implicated in the bottlenose dolphin (tursiops truncatus) mass stranding episode along the northwestern atlantic coast in the late 1980s, and in several more recent worldwide epizootics in different odontoceti species. this study describes a new one step real-time reverse transcription fast polymerase chain reaction (real-time rt-fast pcr) method based on ...201526454114
first gammaherpesvirus detection in a free-living mediterranean bottlenose dolphin.recently, herpes viruses have been detected in different cetacean species from the atlantic and in mediterranean striped dolphins (stenella coeruleoalba). while pathogens such as cetacean morbillivirus have been widely studied following recent epizootics, herpesvirus (hv) distribution and pathogenic effects in cetaceans are still understudied. this study reports the first molecular identification of a gammaherpesvirus in the genital mucosa of a free-living mediterranean bottlenose dolphin (tursi ...201425632684
cetacean morbillivirus in coastal indo-pacific bottlenose dolphins, western australia.cetacean morbillivirus (cemv) has caused several epizootics in multiple species of cetaceans globally and is an emerging disease among cetaceans in australia. we detected cemv in 2 stranded coastal indo-pacific bottlenose dolphins (tursiops aduncus) in western australia. preliminary phylogenetic data suggest that this virus variant is divergent from known strains.201424656203
health and environmental risk assessment project for bottlenose dolphins tursiops truncatus from the southeastern usa. i. infectious diseases.from 2003 to 2015, 360 free-ranging atlantic bottlenose dolphins tursiops truncatus inhabiting the indian river lagoon (irl, n = 246), florida, and coastal waters of charleston (chs, n = 114), south carolina, usa, were captured, given comprehensive health examinations, and released as part of a multidisciplinary and multi-institutional study of individual and population health. the aim of this review is to summarize the substantial health data generated by this study and to examine morbidity bet ...201728737159
host and viral traits predict zoonotic spillover from mammals.the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ...201728636590
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