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preliminary observations on the experimental transmission of chronic wasting disease (cwd) from elk and white-tailed deer to fallow deer.to determine the transmissibility of chronic wasting disease (cwd) to fallow deer (dama dama) and to provide information about clinical course, lesions and suitability of currently used diagnostic procedures for detection of cwd in this species, 13 fawns were inoculated intracerebrally with cwd brain suspension from elk (n=6) or white-tailed deer (n=7). three other fawns were kept as uninfected controls. three cwd-inoculated deer were killed 7.6 months post-inoculation (mpi). none had abnormal p ...200818336829
failure of fallow deer (dama dama) to develop chronic wasting disease when exposed to a contaminated environment and infected mule deer (odocoileus hemionus).we monitored a herd of fallow deer (dama dama) for evidence of prion infection for 7 yr by periodic postmortem examination of animals from the herd. the fallow deer were exposed to the chronic wasting disease (cwd) agent from mule deer by living in a paddock considered contaminated with infectivity from its history of housing cwd infected deer and, after the first year of the study, by comingling with infected mule deer (odocoileus hemionus). at least 8 of 12 mule deer serving as sentinels for p ...201121719844
experimental transmission of chronic wasting disease (cwd) from elk and white-tailed deer to fallow deer by intracerebral route: final report.final observations on experimental transmission of chronic wasting disease (cwd) from elk (cervus elaphus nelsoni) and white-tailed deer (odocoileus virginianus) to fallow deer (dama dama) are reported herein. during the 5-year study, 13 fawns were inoculated intracerebrally with cwd-infected brain material from white-tailed deer (n = 7; group a) or elk (n = 6; group b), and 3 other fawns were kept as uninoculated controls (group c). as described previously, 3 cwd-inoculated deer were euthanized ...201121731188
the role of genetics in chronic wasting disease of north american cervids.chronic wasting disease (cwd) is a major concern for the management of north american cervid populations. this fatal prion disease has led to declines in populations which have high cwd prevalence and areas with both high and low infection rates have experienced economic losses in wildlife recreation and fears of potential spill-over into livestock or humans. research from human and veterinary medicine has established that the prion protein gene (prnp) encodes the protein responsible for transmi ...201222460693
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