| an aspartyl protease inhibitor orthologue expressed by parelaphostrongylus tenuis is immunogenic in an atypical host. | parelaphostrongylus tenuis is a neurotropic nematode common in white-tailed deer (odocoileus virginianus) of eastern north america. this parasite is the causative agent of a debilitating neurologic disease in atypical hosts, including domestic livestock. in order to identify proteins of potential significance in the host-parasite relationship, a cdna library was produced from adult p. tenuis mrna. screening the library with antisera from infected red deer (cervus elaphus elaphus) and immunized a ... | 2002 | 12093670 |
| identification of antigens with potential for immunodiagnosis of parelaphostrongylus tenuis and elaphostrongylus cervi infections in red deer (cervus elaphus elaphus). | red deer (cervus elaphus elaphus) were infected experimentally with parelaphostrongylus tenuis in new brunswick, canada, and with elaphostrongylus cervi in new zealand. excretory-secretory (e-s) antigens from adult p. tenuis were evaluated for their serodiagnostic potential in identifying p. tenuis and heterologous e. cervi infections in a western blot. the antigen recognition profile of sera from animals infected with p. tenuis varied between individuals and with duration of infections, whereas ... | 2002 | 12099432 |
| establishment of adult parelaphostrongylus tenuis, patent infections, and acquired immunity after experimental infection of white-tailed deer (odocoileus virginianus) and red deer (cervus elaphus elaphus). | experimental parelaphostrongylus tenuis infections were established in white-tailed deer (odocoileus virginianus) and an atypical host, red deer (cervus elaphus elaphus). groups of deer were fed 10, 25, or 100 third-stage larvae (l3) of p. tenuis and received a single equivalent challenge exposure at varying intervals. infections were monitored up to 6 yr in white-tailed deer and up to 2.8 yr in red deer. the prepatent period in white-tailed deer varied from 91 to 1,072 days (381 +/- 374) and in ... | 2004 | 15165045 |