Publications

TitleAbstractYear
Filter
PMID
Filter
diagnosis of malignant catarrhal fever by pcr using formalin-fixed, paraffin-embedded tissues.a previously described polymerase chain reaction (pcr) assay (amplification of a 238-bp fragment of ovine herpesvirus 2 [ohv-2] genomic dna) for diagnosis of sheep-associated malignant catarrhal fever (mcf) was adapted for use on formalin-fixed, paraffin-embedded tissues. variables affecting its use were examined. archived tissues from cattle, white-tailed deer (odocoileus virginianus), and bison (bison bison) diagnosed with mcf by clinical signs or histologic lesions were obtained from 2 veteri ...199910098680
serum antibody prevalence of malignant catarrhal fever viruses in seven wildlife species from alaska.blood samples were collected from seven species of free-ranging ungulates in alaska. sera were tested for evidence of exposure to malignant catarrhal fever viruses (mcfv) by means of a competitive enzyme-linked immunosorbent assay. antibody prevalences were as follows: muskox (ovibos moschatus) 100 positive samples of 104 tested (96%); dall sheep (ovis dalli) 212 of 222 (95%); elk (cervus elaphus) 14 of 51 (27%); bison (bison bison) 34 of 197 (17%); caribou (rangifer tarandus) nine of 232 (4%); ...200212238366
polymerase chain reaction and dna sequencing for detection of ovine herpesvirus 2 in american bison (bison bison).serum samples were collected at slaughter from 226 24-30-month-old ranch-raised, clinically normal american bison (bison bison) bulls from north dakota, minnesota, kansas, and manitoba to assess the presence of antibodies to ovine herpesvirus 2 (ohv-2). antibodies to ohv-2 were detected by competitive inhibition enzyme-linked immunosorbent assay in 10 of 226 (4.40%) samples. polymerase chain reaction (pcr) analysis of sera positive for ohv-2 dna demonstrated a 238 kilobase fragment. the nucleoti ...200212680642
seroprevalence of ohv-2, bvdv, bhv-1, and brsv in ranch-raised bison (bison bison).serum samples were collected at slaughter from 226 24-30-month-old american bison (bison bison) bulls from kansas, minnesota, north dakota, and manitoba and assayed for antibodies to ovine herpesvirus type-2 (ohv-2), bovine viral diarrhea virus (bvdv), bovine herpesvirus type-1 (bhv-1), and bovine respiratory syncytial virus (brsv). antibodies were detected by serum neutralization for bvdv, bhv-1, and brsv, while antibodies to ohv-2 were detected by competitive inhibition-elisa (ci-elisa). detec ...200212680649
an outbreak of sheep-associated malignant catarrhal fever in bison (bison bison) after exposure to sheep at a public auction sale.an outbreak of malignant catarrhal fever (mcf) among bison sold at an auction market was studied for an 18-month period. forty-five of 163 bison submitted for sale from 8 different bison farms died on 7 other destination farms. the outbreak began on day 50 after the sale, peaked between days 60 and 70, and ended on day 220. twenty-one dead bison were confirmed to be mcf cases by clinical histories, pathology, and detection of ovine herpesvirus-2 dna in their tissues with polymerase chain reactio ...200515690951
resistance to malignant catarrhal fever in american bison (bison bison) is associated with mhc class iia polymorphisms.the rhadinovirus ovine herpesvirus-2 (ovhv-2) is the most common causative agent of malignant catarrhal fever (mcf) in clinically susceptible ruminants including cattle and bison. american bison (bison bison) are highly susceptible to clinical mcf. nevertheless, approximately 20% of bison on ranches or in feedlots become infected with the virus without developing clinical disease. defining the genetic basis for differences in susceptibility between bison could facilitate development of improved ...200717326800
intra-nasal inoculation of american bison (bison bison) with ovine herpesvirus-2 (ovhv-2) reliably reproduces malignant catarrhal fever.sheep-associated malignant catarrhal fever (mcf) due to infection with ovine herpesvirus 2 (ovhv-2) is common in commercial herds of american bison ( bison bison). inability to propagate ovhv-2 in vitro has been a constraint on experimental studies of the disease. we sought to establish whether nasal secretions from sheep that shed ovhv-2 might induce the disease in bison and to define a minimum challenge dose. fourteen bison were nebulized with sheep nasal sections containing 10(3)-10(7) ovhv-2 ...200717846237
malignant catarrhal fever in a captive american bison (bison bison) in italy.malignant catarrhal fever (mcf) is a fatal, systemic disease of cattle and other domestic and wild ruminants that, in europe, is caused by ovine herpesvirus 2 (ovhv-2). american bison (bison bison) are highly susceptible to the disease. an adult american bison, housed in a zoo in southern italy in close cohabitation with a group of domestic sheep (ovis aries aries) displayed clinical signs that resembled the acute form of mcf. by real-time polymerase chain reaction, ovhv-2 dna was detected intra ...200818987244
experimental nebulization of american bison (bison bison) with low doses of ovine herpesvirus 2 from sheep nasal secretions.malignant catarrhal fever (mcf), caused by ovine herpesvirus 2 (ovhv-2), is an important cause of mortality in ranched american bison and domestic cattle in north america. previous studies showed that bison can be infected by intranasal nebulization with sheep nasal secretions containing ovhv-2 and provided preliminary information on viral doses required for infection and disease progression. the goals of this study were to establish optimal minimal infectious and minimal lethal doses of ovhv-2 ...201020018461
cd8(+)/perforin(+)/wc1(-) gammadelta t cells, not cd8(+) alphabeta t cells, infiltrate vasculitis lesions of american bison (bison bison) with experimental sheep-associated malignant catarrhal fever.sheep-associated malignant catarrhal fever (sa-mcf) caused by ovine herpesvirus-2 (ovhv-2), a gamma-herpesvirus in the macavirus genus, is a fatal disease associated with lymphoproliferation, lymphocytic vasculitis, and mucosal ulceration in clinically susceptible species. sa-mcf is an important threat to american bison (bison bison) due to their high susceptibility to this disease. currently, the pathogenesis of disease in sa-mcf is poorly understood, and the immunophenotype of lymphocytes that ...201020413164
fibroblasts express ovhv-2 capsid protein in vasculitis lesions of american bison (bison bison) with experimental sheep-associated malignant catarrhal fever.american bison (bison bison) are particularly susceptible to developing fatal sheep-associated malignant catarrhal fever (sa-mcf) caused by ovine herpesvirus-2 (ovhv-2), a γ-herpesvirus in the macavirus genus. this generally fatal disease is characterized by lymphoproliferation, vasculitis, and mucosal ulceration in american bison, domestic cattle (bos taurus), and other clinically susceptible species which are considered non-adapted, dead-end hosts. the pathogenesis and cellular tropism of ovhv ...201323953727
malignant catarrhal fever: an emerging disease in the african buffalo (syncerus caffer).within the tribe bovini in the subfamily bovinae, the water buffalo (bubalus bubalis), american bison (bison bison), european bison (bubalus bonasus) and yak (bos grunniens) are recognized as species highly susceptible to malignant catarrhal fever (mcf). in contrast, the lack of reports describing clinical mcf in the african buffalo (syncerus caffer) whether free ranging or captive has led to a perception that african buffaloes are resistant to mcf. during the last decade, several cases of mcf i ...201523957274
malignant catarrhal fever in american bison (bison bison) experimentally infected with alcelaphine herpesvirus 2.malignant catarrhal fever (mcf), due to ovine herpesvirus 2 (ovhv-2), causes appreciable death loss in ranched bison (bison bison) throughout north america. no vaccine exists to protect animals from disease. since ovhv-2 has not been propagated in vitro, one strategy to develop a modified live vaccine is to use a closely related, non-pathogenic member of the malignant catarrhal fever virus family as a vector expressing potentially protective ovhv-2 epitopes. to date, no controlled experimental c ...201424803260
characterization of bison bison major histocompatibility complex class iia haplotypes.american bison (bison bison) and domestic cattle (bos taurus and bos indicus) evolved from a common ancestor 1-1.4 million years ago. nevertheless, they show dramatic differences in their susceptibility to infectious diseases, including malignant catarrhal fever (mcf). although bison are highly susceptible to ovine herpesvirus-2 (ovhv-2) associated mcf, about 20% of healthy domesticated and wild bison are positive for ovhv-2 antibody. we are interested in testing the hypothesis that, within the ...200516331512
malignant catarrhal fever in a bison (bison bison) feedlot, 1993-2000.a fatal enteric syndrome was identified in american bison (bison bison) at a large feedlot in the american midwest in early 1998. an estimated 150 bison died of the syndrome between january 1998 and december 1999. the syndrome was identified as malignant catarrhal fever (mcf), primarily the alimentary form. clinical onset was acute, and most affected bison died within 1-3 days; none recovered. consistent lesions were hemorrhagic cystitis, ulcerative enterotyphlocolitis, and arteritis-phlebitis. ...200212033673
Displaying items 1 - 15 of 15