in vitro activity of the new triazole voriconazole (uk-109,496) against opportunistic filamentous and dimorphic fungi and common and emerging yeast pathogens.the in vitro antifungal activity of a new triazole derivative, voriconazole, was compared with those of itraconazole and amphotericin b against 67 isolates of aspergillus flavus, aspergillus fumigatus, bipolaris spp., fusarium oxysporum, fusarium solani, pseudallescheria boydii, rhizopus arrhizus, blastomyces dermatitidis, histoplasma capsulatum, and sporothrix schenckii. the in vitro activities of voriconazole were also compared with those of amphotericin b, fluconazole, and itraconazole agains ...19989431946
successful treatment of systemic geotrichum capitatum infection by liposomal amphotericin-b, itraconazole, and voriconazole in a japanese man.severe systemic geotrichum capitatum (g. capitatum) infection is rare, especially in japan. g. capitatum infection has been reported mainly in immunocompromised patients and the prognosis is poor with a mortality rate of approximately 50-75%. here, we report a japanese case of systemic g. capitatum infection in a severe neutropenic patient who was receiving chemotherapy for acute myelogeneous leukemia with multilineage dysplasia. g. capitatum was isolated from blood cultures, and also formed mul ...201021088357
blastoschizomyces capitatus keratitis and melting in a corneal report: we present the first case, to our knowledge, of blastoschizomyces capitatus keratitis and melting in a corneal graft. an 80-year-old man was treated for a large, severe corneal abscess and melting in the corneal graft of his right eye. medical history was negative for hematologic disorders. urgent penetrating keratoplasty was performed. comments: corneal cultures grew b. capitatus. systemic fluconazole and systemic and topical amphotericin b treatment were started. three months afte ...200617224964
disseminated trichosporon capitatum infection in an immunosuppressed host.trichosporon is a frequent cause of superficial mycotic infections but has rarely been associated with invasive disease. a patient undergoing bone marrow transplantation who died from disseminated trichosporon capitatum infection with endocarditis is reported, and the clinical spectrum of human infection caused by fungi of this genus is reviewed. to our knowledge, this is the first reported case of clearly invasive disease caused by this specific organism and emphasizes the expanding spectrum of ...1977332101
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