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west nile virus viremia in eastern chipmunks (tamias striatus) sufficient for infecting different mosquitoes.in eastern chipmunks (tamias striatus) inoculated intramuscularly with 101.5 to 105.7 pfu of west nile virus (wnv), serum titers developed sufficient to infect aedes triseriatus (say), ae. vexans (meigen), and culex pipiens (l.). mean titers (95% confidence interval) of 8 chipmunks were 103.9(3.3-4.5), 106.7(6.4-7.0), and 105.8(4.1-7.5) pfu/ml on days 1-3 postinoculation (p.i.) and 105.8 pfu/ml in 1 chipmunk on day 4 p.i. mean estimated days that wnv titers were >104.8 and >105.6 were 1.7 (1.1-2 ...200717553220
west nile virus associations in wild mammals: a synthesis.exposures to west nile virus (wnv) have been documented in a variety of wild mammals in both the new and old worlds. this review tabulates at least 100 mammal species with evidence of wnv exposure. many of these exposures were detected in free-ranging mammals, while several were noted in captive individuals. in addition to exposures, this review discusses experimental infections in terms of the potential for reservoir competence of select wild mammal species. overall, few experimental infections ...201323212739
host and viral traits predict zoonotic spillover from mammals.the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ...201728636590
predicting the global mammalian viral sharing network using phylogeography.understanding interspecific viral transmission is key to understanding viral ecology and evolution, disease spillover into humans, and the consequences of global change. prior studies have uncovered macroecological drivers of viral sharing, but analyses have never attempted to predict viral sharing in a pan-mammalian context. using a conservative modelling framework, we confirm that host phylogenetic similarity and geographic range overlap are strong, nonlinear predictors of viral sharing among ...202032385239
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