experimental plague in rock squirrels, spermophilus variegatus (erxleben).experimental infections with yersinia pestis were followed in groups of rock squirrels. development of coagulopathy and pneumonia were observed in 2-4% and 11-12% of the test animals, respectively. susceptibility to experimental infection was heterogeneous with some animals surviving inoculation with large numbers of organisms and others succumbing after inoculation with small numbers. production and longevity of serum antibody titers, as measured by passive hemagglutination tests, were variable ...19854032620
source of host blood affects prevalence of infection and bacterial loads of yersinia pestis in fleas.yersinia pestis, the etiological agent of plague, is transmitted by multiple flea species. previous studies have reported wide variability in transmission efficiency among competent vectors. however, it is unclear to what extent such variation is explained by methodological differences among studies. to optimize an artificial feeding system where fleas are infected with controlled numbers of y. pestis under standardized laboratory conditions that could be used to systematically compare vector ef ...200818826038
yersinia pestis infection and laboratory conditions alter flea-associated bacterial communities.we collected oropsylla montana from rock squirrels, spermophilus varigatus, and infected a subset of collected fleas with yersinia pestis, the etiological agent of plague. we used bar-tagged dna pyrosequencing to characterize bacterial communities of wild, uninfected controls and infected fleas. bacterial communities within y. pestis-infected fleas were substantially more similar to one another than communities within wild or control fleas, suggesting that infection alters the bacterial communit ...201222895162
small-scale die-offs in woodrats support long-term maintenance of plague in the u.s. southwest.our longitudinal study of plague dynamics was conducted in north-central new mexico to identify which species in the community were infected with plague, to determine the spatial and temporal patterns of the dynamics of plague epizootics, and to describe the dynamics of yersinia pestis infection within individual hosts. a total of 3156 fleas collected from 535 small mammals of 8 species were tested for y. pestis dna. nine fleas collected from six southern plains woodrats (neotoma micropus) and f ...201728792853
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