| detection and enumeration of leishmania in sand flies using agar-based media. | an agar plating technique was used to determine the number of amastigotes ingested by lutzomyia longipalpis fed on papules on mesocricetus auratus caused by leishmania mexicana amazonensis and on lesions on mystromys albicaudatus caused by leishmania braziliensis panamensis. the technique involved homogenizing sand flies after bloodfeeding on the infected animals and spreading the homogenate over the surface of agar plates. a great variation in the number of amastigotes ingested by individual sa ... | 1987 | 3688307 |
| experimental cutaneous leishmaniasis. i. infection of albino mice and syrian hamsters by leishmania mexicana. | | 1965 | 5892041 |
| a combination dna vaccine encoding nucleoside hydrolase 36 and glycoproteine 63 protects female but not male hamsters against leishmania mexicana. | leishmaniasis is a group of diseases caused by protozoan parasites of the leishmania genus. previous studies have shown that a dna vaccine encoding leishmania donovani antigen nucleoside hydrolase 36 and l. mexicana glycoprotein 63 is protective in mice. we investigated here the efficacy of this dna vaccine to induce protection in golden hamsters. male hamsters were more susceptible to infection by leishmania mexicana than females. following immunization with two doses of the dna vaccine, only f ... | 2009 | 19839269 |
| immunization with the dna-encoding n-terminal domain of proteophosphoglycan of leishmania donovani generates th1-type immunoprotective response against experimental visceral leishmaniasis. | leishmania produce several types of mucin-like glycoproteins called proteophosphoglycans (ppgs) which exist as secretory as well as surface-bound forms in both promastigotes and amastigotes. the structure and function of ppgs have been reported to be species and stage specific as in the case of leishmania major and leishmania mexicana; there has been no such information available for leishmania donovani. we have recently demonstrated that ppg is differentially expressed in sodium stibogluconate- ... | 2009 | 19542458 |
| leishmania species: comparative ultrastructure of experimental nodules and diffuse human cutaneous lesions in american leishmaniases. | experimental nodules of american leishmaniases were obtained by inoculating 0.1-1 x 10(5) amastigotes into the dorsum of the hindpaws of golden hamsters and of c57bl/6j mice. the amastigotes were obtained by biopsy of lesions in six human cases of cutaneous leishmaniases and were serially maintained in golden hamsters and in a fetal calf serum-containing medium. human nodules were obtained by biopsy from several patients with diffuse cutaneous leishmaniases, always prior to treatment. within the ... | 1983 | 6852172 |
| leishmania mexicana complex: human infections in the republic of panama. | parasites of the genus leishmania responsible for human cutaneous leishmaniasis in the new world form 2 major taxonomic divisions: the leishmania braziliensis and the l. mexicana complexes. we report the isolation and characterization of the l. mexicana complex among humans in the republic of panama. characterization was based on parasite morphology, pathogenesis in infected golden hamsters, cellulose acetate isoenzyme electrophoretic mobilities, and membrane-specific monoclonal antibodies using ... | 1990 | 2267966 |
| leishmania braziliensis and leishmania mexicana: experimental cutaneous infections in golden hamsters. | | 1979 | 437020 |