induction of hepatitis in adult syrian hamster by h-1 virus.the induction of hepatitis in adult hamster by h-1 virus was documented by demonstrating an increase in serum sgot and sgpt at 3-9 wk postinoculation. the electrophoresis pattern of ldh isoenzymes showed a marked increase in the liver fraction (fraction 5) indicating liver damage in infected hamsters. the pathology displayed in diseased livers revealed a focal degeneration of hepatic cells although infiltration of white cells was not observed. h-1 virus is apparently capable of producing hepatit ...19751144433
inhibition of 7,12-dimethylbenz(a)anthracene-induced tumors in syrian hamsters by prior infection with h-1 parvovirus.hamsters, given injections s.c. at birth of h-1 parvovirus and 1 month later given a single injection of 7,12-dimethylbenz(a)anthracene, had a 38% tumor incidence compared with a 95% incidence in animals receiving 7,12-dimethylbenz(a)anthracene alone. thus, h-1 which, it has already been shown, invokes a resistance to the incidence of spontaneous and adenovirus-induced neoplasms in hamsters also produces a suppression of a carcinogen-induced tumor in these animals; this suggests that the h-1-ind ...19826805941
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