Publications

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down regulation of macrophage activation in brugia pahangi-infected jirds (meriones unguiculatus).the macrophage is a major component of the inflammatory response induced by lymphatic tissue-dwelling filariae. intraperitoneal (i.p.) infections with brugia pahangi in mongolian gerbils, or jirds (meriones unguiculatus), induce a peritoneal inflammatory response characterized by accumulation of numerous macrophages and fewer eosinophils. this inflammatory response is associated with the release of microfilariae by female worms. the aim of this study was to investigate the activation state of th ...19989488396
gerbils (meriones unguiculatus) are highly susceptible to oral infection with neospora caninum oocysts.laboratory-reared gerbils (meriones unguiculatus) were found to be highly susceptible to oral infection with neospora caninum (nc-liv strain) oocysts. gerbils fed approximately 1000 oocysts became sick or died at 6-13 days post feeding of oocysts (pfo). n. caninum was isolated in cell culture and from gamma-interferon-knockout mice inoculated with homogenates of mesenteric lymph nodes of gerbils examined as early as 1 day pfo. numerous n. caninum tachyzoites were found in ulcerative lesions in t ...200010685849
confirmed clinical neospora caninum infection in a boxer puppy from argentina.generalized neosporosis was diagnosed in a 2-month-old boxer puppy. the dog had a history of progressive paralysis and muscle atrophy, followed by cervical weakness, stiff jaws and dysphagia. the dog had a 1:12,800 antibody titer for neospora caninum and was negative for antibodies to toxoplasma gondii by the indirect fluorescent antibody test (ifat). after euthanasia a complete necropsy was carried out. the puppy had a megaesophagus. microscopically, tachyzoites and tissue cysts were observed i ...200515978728
incidence of neospora caninum and other intestinal protozoan parasites in populations of swiss dogs.the protozoan parasite neospora caninum is one of the most important abortifacient organisms in cattle worldwide. the dog is known to act as definitive host although its potential role as infection source for bovines still remains unelucidated. the aim of the present study was to compile initial epidemiological data on the prevalence and incidence of n. caninum in swiss dogs acting as definitive hosts. thus, 249 swiss dogs were investigated coproscopically in monthly intervals over a period of 1 ...200616564131
itraq-based differential proteomic analysis in mongolian gerbil brains chronically infected with toxoplasma gondii.the aim of our study was to detect differentially regulated proteins and specific signaling pathways in mongolian gerbil brains during chronic toxoplasma gondii (t.gondii) pru strain infection. we use a itraq-based strategy to detecte 4935 proteins, out of which 110 proteins were differentially expressed (>/=2.0-fold, p value <0.05) when the brain of gerbils infected with t.gondii was compared to control brain tissues. we confirmed the authenticity and the accuracy of itraq results through quant ...201728323244
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