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experimental infection of ground squirrels (spermophilus tridecemlineatus) with monkeypox virus.a proposed new small-animal (rodent) model for studying the pathogenesis and treatment of severe orthopoxvirus infections is described. thirteen-lined ground squirrels (spermophilus tridecemlineatus) were infected intraperitoneally and intranasally with monkeypox virus (mpxv). a fulminant illness developed in all animals, and they died 6-9 days after infection. virus was cultured from the blood and oropharynx several days before death; at necropsy, all of the organs tested contained relatively h ...200415498157
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