canine asct1 and asct2 are functional receptors for rd-114 virus in dogs.all domestic cats have an infectious endogenous retrovirus, termed rd-114 virus. recently, we and others found that several live attenuated vaccines for dogs were contaminated with infectious rd-114 virus. in this study, we confirmed that the rd-114 virus efficiently infected and proliferated well in canine primary kidney cells as well as three canine cell lines tested. further, we identified canine asct1 and asct2, sodium-dependent neutral amino acid transporters, as rd-114 virus receptors. ...201122131312
activation in vivo of retroperitoneal fibromatosis-associated herpesvirus, a simian homologue of human herpesvirus-8.retroperitoneal fibromatosis-associated herpesvirus of rhesus macaques (rfhvmm) is a gammaherpesvirus closely related to human herpesvirus-8 (hhv-8), which is thought to be a necessary cofactor for the development of kaposi's sarcoma (ks) in humans. here, rfhvmm infection of rhesus macaques exposed to the d-type retrovirus simian retrovirus-2 (srv-2) is described. development of srv-2 viraemia, infection with simian immunodeficiency virus or administration of cyclosporin a could result in persis ...199910073709
transmission of simian acquired immunodeficiency syndrome with a type d retrovirus: immunological aspects.simian acquired immunodeficiency syndrome (saids) was transmitted to four of four rhesus macaques with blood from rhesus macaques naturally infected with a type d retrovirus, simian retrovirus-2 (srv-2). three of the four blood recipients died with saids at 13, 15, and 26 weeks postinoculation. the fourth animal is alive with saids. all four test monkeys became viremic and produced antiviral antibody. none of the inoculated monkeys produced measureable neutralizing antibody to srv-2. the survivo ...19863780059
intestinal stromal tumors in a simian immunodeficiency virus-infected, simian retrovirus-2 negative rhesus macaque (macaca mulatta).multifocal submucosal stromal tumors were diagnosed in a 5.5-year-old rhesus macaque (macaca mulatta) experimentally infected with simian immunodeficiency virus, strain sivsme660, and cd4+ t cell depleted. the animal was negative for simian retroviruses, srv-1, -2, and -5. polymerase chain reaction analysis of dna from tumor and spleen tissue revealed abundant, preferential presence of retroperitoneal fibromatosis herpesvirus, the macaque homologue of the kaposi sarcoma-associated herpesvirus (h ...200515872392
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