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full-length genome sequences of two sars-like coronaviruses in horseshoe bats and genetic variation analysis.bats were recently identified as natural reservoirs of sars-like coronavirus (sl-cov) or sars coronavirus-like virus. these viruses, together with sars coronaviruses (sars-cov) isolated from human and palm civet, form a distinctive cluster within the group 2 coronaviruses of the genus coronavirus, tentatively named group 2b (g2b). in this study, complete genome sequences of two additional group 2b coronaviruses (g2b-covs) were determined from horseshoe bat rhinolophus ferrumequinum (g2b-cov rf1) ...200617030870
molecular epidemiology, evolution and phylogeny of sars coronavirus.shortly after its emergence in southern china in 2002/2003, severe acute respiratory syndrome coronavirus (sars-cov) was confirmed to be the cause of sars. subsequently, sars-related covs (sarsr-covs) were found in palm civets from live animal markets in guangdong and in various horseshoe bat species, which were believed to be the ultimate reservoir of sarsr-cov. till november 2018, 339 sarsr-cov genomes have been sequenced, including 274 from human, 18 from civets and 47 from bats [mostly from ...201930844511
severe acute respiratory syndrome (sars) coronavirus orf8 protein is acquired from sars-related coronavirus from greater horseshoe bats through recombination.despite the identification of horseshoe bats as the reservoir of severe acute respiratory syndrome (sars)-related coronaviruses (sarsr-covs), the origin of sars-cov orf8, which contains the 29-nucleotide signature deletion among human strains, remains obscure. although two sars-related rhinolophus sinicus bat covs (sarsr-rs-batcovs) previously detected in chinese horseshoe bats (rhinolophus sinicus) in yunnan, rsshc014 and rs3367, possessed 95% genome identities to human and civet sarsr-covs, th ...201526269185
a real-time pcr assay for bat sars-like coronavirus detection and its application to italian greater horseshoe bat faecal sample surveys.bats are source of coronaviruses closely related to the severe acute respiratory syndrome (sars) virus. numerous studies have been carried out to identify new bat viruses related to sars-coronavirus (bat-sars-like covs) using a reverse-transcribed-polymerase chain reaction assay. however, a qualitative pcr could underestimate the prevalence of infection, affecting the epidemiological evaluation of bats in viral ecology. in this work an sybr green-real time pcr assay was developed for diagnosing ...201122654650
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