irf7 in the australian black flying fox, pteropus alecto: evidence for a unique expression pattern and functional the only flying mammal, bats harbor a number of emerging and re-emerging viruses, many of which cause severe diseases in humans and other mammals yet result in no clinical symptoms in bats. as the master regulator of the interferon (ifn)-dependent immune response, ifn regulatory factor 7 (irf7) plays a central role in innate antiviral immunity. to explore the role of bat irf7 in the regulation of the ifn response, we performed sequence and functional analysis of irf7 from the pteropid bat, pt ...201425100081
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