| host and viral traits predict zoonotic spillover from mammals. | the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ... | 2017 | 28636590 |
| insights into persistence mechanisms of a zoonotic virus in bat colonies using a multispecies metapopulation model. | rabies is a worldwide zoonosis resulting from lyssavirus infection. in europe, eptesicus serotinus is the most frequently reported bat species infected with lyssavirus, and thus considered to be the reservoir of european bat lyssavirus type 1 (eblv-1). to date, the role of other bat species in eblv-1 epidemiology and persistence remains unknown. here, we built an eblv-1-transmission model based on local observations of a three-cave and four-bat species (myotis capaccinii, myotis myotis, miniopte ... | 2014 | 24755619 |
| temporal dynamics of european bat lyssavirus type 1 and survival of myotis myotis bats in natural colonies. | many emerging rna viruses of public health concern have recently been detected in bats. however, the dynamics of these viruses in natural bat colonies is presently unknown. consequently, prediction of the spread of these viruses and the establishment of appropriate control measures are hindered by a lack of information. to this aim, we collected epidemiological, virological and ecological data during a twelve-year longitudinal study in two colonies of insectivorous bats (myotis myotis) located i ... | 2007 | 17593965 |
| european bat lyssavirus infection in spanish bat populations. | from 1992 to 2000, 976 sera, 27 blood pellets, and 91 brains were obtained from 14 bat species in 37 localities in spain. specific anti-european bat lyssavirus 1 (ebl1)-neutralizing antibodies have been detected in myotis myotis, miniopterus schreibersii, tadarida teniotis, and rhinolophus ferrumequinum in the region of aragon and the balearic islands. positive results were also obtained by nested reverse transcription-polymerase chain reaction on brain, blood pellet, lung, heart, tongue, and es ... | 2002 | 11971777 |
| molecular and serological survey of lyssaviruses in croatian bat populations. | rabies is the only known zoonotic disease of bat origin in europe. the disease is caused by species belonging to the genus lyssavirus. five lyssavirus species, i.e., european bat lyssavirus (eblv)-1, eblv-2, bokeloh bat lyssavirus, lleida bat lyssavirus, and west caucasian bat virus, have been identified in european bats. more recently, a proposed sixth species, kotalahti bat lyssavirus, was detected. thus, in this study, active surveillance was initiated in order to obtain insights into the pre ... | 2018 | 30189884 |
| active and passive surveillance for bat lyssaviruses in italy revealed serological evidence for their circulation in three bat species. | the wide geographical distribution and genetic diversity of bat-associated lyssaviruses (lysvs) across europe suggest that similar viruses may also be harboured in italian insectivorous bats. indeed, bats were first included within the passive national surveillance programme for rabies in wildlife in the 1980s, while active surveillance has been performed since 2008. the active surveillance strategies implemented allowed us to detect neutralizing antibodies directed towards european bat 1 lyssav ... | 2018 | 30511606 |
| longitudinal survey of two serotine bat (eptesicus serotinus) maternity colonies exposed to eblv-1 (european bat lyssavirus type 1): assessment of survival and serological status variations using capture-recapture models. | this study describes two longitudinal serological surveys of european bat lyssavirus type 1 (eblv-1) antibodies in serotine bat (eptesicus serotinus) maternity colonies located in the north-east of france. this species is currently considered as the main eblv-1 reservoir. multievent capture-recapture models were used to determine the factors influencing bat rabies transmission as this method accounts for imperfect detection and uncertainty in disease states. considering the period of study, anal ... | 2017 | 29149215 |