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broad and temperature independent replication potential of filoviruses on cells derived from old and new world bat species.filoviruses are strongly associated with several species of bats as their natural reservoirs. in this study, we determined the replication potential of all filovirus species: marburg marburgvirus, taï forest ebolavirus, reston ebolavirus, sudan ebolavirus, zaire ebolavirus, and bundibugyo ebolavirus. filovirus replication was supported by all cell lines derived from 6 old and new world bat species: the hammer-headed fruit bat, buettikofer's epauletted fruit bat, the egyptian fruit bat, the jamai ...201627354372
large serological survey showing cocirculation of ebola and marburg viruses in gabonese bat populations, and a high seroprevalence of both viruses in rousettus aegyptiacus.ebola and marburg viruses cause highly lethal hemorrhagic fevers in humans. recently, bats of multiple species have been identified as possible natural hosts of zaire ebolavirus (zebov) in gabon and republic of congo, and also of marburgvirus (marv) in gabon and democratic republic of congo.200919785757
spatial and temporal patterns of zaire ebolavirus antibody prevalence in the possible reservoir bat species.to characterize the distribution of zaire ebolavirus (zebov) infection within the 3 bat species (epomops franqueti, hypsignathus monstrosus, and myonycteris torquata) that are possible reservoirs, we collected 1390 bats during 2003-2006 in gabon and the republic of the congo. detection of zebov immunoglobulin g (igg) in 40 specimens supports the role of these bat species as the zebov reservoirs. zebov igg prevalence rates (5%) were homogeneous across epidemic and nonepidemic regions during outbr ...200717940947
comparative phylogeography of african fruit bats (chiroptera, pteropodidae) provide new insights into the outbreak of ebola virus disease in west africa, 2014-2016.both ebolavirus and marburgvirus were detected in several fruit bat species of the family pteropodidae, suggesting that this taxon plays a key role in the life cycle of filoviruses. after four decades of zaire ebolavirus (zebov) outbreaks in central africa, the virus was detected for the first time in west africa in 2014. to better understand the role of fruit bats as potential reservoirs and circulating hosts between central and west africa, we examine here the phylogeny and comparative phyloge ...201727746072
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