| large serological survey showing cocirculation of ebola and marburg viruses in gabonese bat populations, and a high seroprevalence of both viruses in rousettus aegyptiacus. | ebola and marburg viruses cause highly lethal hemorrhagic fevers in humans. recently, bats of multiple species have been identified as possible natural hosts of zaire ebolavirus (zebov) in gabon and republic of congo, and also of marburgvirus (marv) in gabon and democratic republic of congo. | 2009 | 19785757 |
| spatial and temporal patterns of zaire ebolavirus antibody prevalence in the possible reservoir bat species. | to characterize the distribution of zaire ebolavirus (zebov) infection within the 3 bat species (epomops franqueti, hypsignathus monstrosus, and myonycteris torquata) that are possible reservoirs, we collected 1390 bats during 2003-2006 in gabon and the republic of the congo. detection of zebov immunoglobulin g (igg) in 40 specimens supports the role of these bat species as the zebov reservoirs. zebov igg prevalence rates (5%) were homogeneous across epidemic and nonepidemic regions during outbr ... | 2007 | 17940947 |
| ebolavirus and other filoviruses. | since ebola fever emerged in central africa in 1976, a number of studies have been undertaken to investigate its natural history and to characterize its transmission from a hypothetical reservoir host(s) to humans. this research has comprised investigations on a variety of animals and their characterization as intermediate, incidental, amplifying, reservoir, or vector hosts. a viral transmission chain was recently unveiled after a long absence of epidemic ebola fever. animal trapping missions we ... | 2007 | 17848072 |
| survey of ebola viruses in frugivorous and insectivorous bats in guinea, cameroon, and the democratic republic of the congo, 2015-2017. | to clarify the role of bats in the ecology of ebola viruses, we assessed the prevalence of ebola virus antibodies in a large-scale sample of bats collected during 2015-2017 from countries in africa that have had previous ebola outbreaks (guinea, the democratic republic of the congo) or are at high risk for outbreaks (cameroon). we analyzed 4,022 blood samples of bats from >12 frugivorous and 27 insectivorous species; 2-37 (0.05%-0.92%) bats were seropositive for zaire and 0-30 (0%-0.75%) bats fo ... | 2018 | 30307845 |
| [bats and other reservoir hosts of filoviridae. danger of epidemic on the african continent?--a deductive literature analysis]. | ebola and marburg virus, forming the filoviridae family, cause hemorrhagic fever in countries of sub-saharan africa. these viral diseases are characterized by a sudden epidemic occurrence as well as a high lethality. even though a reservoir host has not been approved yet, literature indicates the order of bats (chiroptera) as a potential reservoir host. significant references lead to a delineation of a hypothetical ecosystem of filoviridae including chiroptera. igg-specific ebola-zaire antibodie ... | 2010 | 20924703 |
| broad and temperature independent replication potential of filoviruses on cells derived from old and new world bat species. | filoviruses are strongly associated with several species of bats as their natural reservoirs. in this study, we determined the replication potential of all filovirus species: marburg marburgvirus, taï forest ebolavirus, reston ebolavirus, sudan ebolavirus, zaire ebolavirus, and bundibugyo ebolavirus. filovirus replication was supported by all cell lines derived from 6 old and new world bat species: the hammer-headed fruit bat, buettikofer's epauletted fruit bat, the egyptian fruit bat, the jamai ... | 2016 | 27354372 |
| comparative phylogeography of african fruit bats (chiroptera, pteropodidae) provide new insights into the outbreak of ebola virus disease in west africa, 2014-2016. | both ebolavirus and marburgvirus were detected in several fruit bat species of the family pteropodidae, suggesting that this taxon plays a key role in the life cycle of filoviruses. after four decades of zaire ebolavirus (zebov) outbreaks in central africa, the virus was detected for the first time in west africa in 2014. to better understand the role of fruit bats as potential reservoirs and circulating hosts between central and west africa, we examine here the phylogeny and comparative phyloge ... | 2017 | 27746072 |
| lek-associated movement of a putative ebolavirus reservoir, the hammer-headed fruit bat (hypsignathus monstrosus), in northern republic of congo. | the biology and ecology of africa's largest fruit bat remains largely understudied and enigmatic despite at least two highly unusual attributes. the acoustic lek mating behavior of the hammer-headed bat (hypsignathus monstrosus) in the congo basin was first described in the 1970s. more recently molecular testing implicated this species and other african bats as potential reservoir hosts for ebola virus and it was one of only two fruit bat species epidemiologically linked to the 2008 luebo, democ ... | 2019 | 31574111 |