neotropical primary bat cell lines show restricted dengue virus replication.dengue is the most widespread arboviral disease affecting humans. bats are recognized carriers of emerging viral zoonoses and have been proposed as dengue reservoirs, since rna/ns1 and/or antiviral antibodies have been detected. yet, experimental inoculation of artibeus bats failed to show virus replication. this conflicting results prevent drawing further conclusions of whether bats sustain dengue infection. to test bat cellular permissivity to dengue infection, we established primary bat embry ...201728131369
host and viral traits predict zoonotic spillover from mammals.the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ...201728636590
ectoparasitic hematophagous dipters: potential reservoirs of dengue virus?recently, the presence of antibodies and dengue virus (dv) rna in neotropical wild mammals, including desmodus rotundus, was reported. in a previous study, dv was also found in a high percentage (39.6%) of ectoparasitic hematophagous dipters specifics of these hematophagous bats. in order to verify the susceptibility of these ectoparasites to dv, in this work experimental infections with vd2 of organs explants of strebla wiedemanni and of melophagus ovinus were performed using c6/36 cells as con ...201729099114
detection of dengue virus in bat flies (diptera: streblidae) of common vampire bats, desmodus rotundus, in progreso, hidalgo, mexico.blood-feeding arthropods play a major role in the transmission of several flaviviruses, which represent an important problem for human health. currently, dengue is one of the most important arboviral emerging diseases worldwide. furthermore, some previous studies have reported the presence of viral nucleic acids and antibodies against dengue virus (denv) in wild animals. our knowledge of the role played by wildlife reservoirs in the sylvatic transmission and maintenance of denv remains limited. ...201829232534
predicting the global mammalian viral sharing network using phylogeography.understanding interspecific viral transmission is key to understanding viral ecology and evolution, disease spillover into humans, and the consequences of global change. prior studies have uncovered macroecological drivers of viral sharing, but analyses have never attempted to predict viral sharing in a pan-mammalian context. using a conservative modelling framework, we confirm that host phylogenetic similarity and geographic range overlap are strong, nonlinear predictors of viral sharing among ...202032385239
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