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aspergillus felis sp. nov., an emerging agent of invasive aspergillosis in humans, cats, and dogs.we describe a novel heterothallic species in aspergillus section fumigati, namely a. felis (neosartorya-morph) isolated from three host species with invasive aspergillosis including a human patient with chronic invasive pulmonary aspergillosis, domestic cats with invasive fungal rhinosinusitis and a dog with disseminated invasive aspergillosis. disease in all host species was often refractory to aggressive antifungal therapeutic regimens. four other human isolates previously reported as a. virid ...201323798996
feline aspergillosis.feline aspergillosis includes sinonasal aspergillosis (sna), sino-orbital aspergillosis (soa), other focal invasive forms, and disseminated disease. soa is an invasive mycosis that is being increasingly recognized, and is most commonly caused by a recently discovered pathogen aspergillus felis. sna can be invasive or noninvasive and is most commonly caused by aspergillus fumigatus and aspergillus niger. molecular methods are required to correctly identify the fungi that cause sna and soa. sna ha ...201424268333
polyphasic characterization of fungal isolates from a published case of invasive aspergillosis reveals misidentification of aspergillus felis as aspergillus viridinutans. 201424469682
computed tomographic features of feline sino-nasal and sino-orbital aspergillosis.feline upper respiratory tract aspergillosis (urta) occurs as two distinct anatomical forms, namely, sino-nasal aspergillosis (sna) and sino-orbital aspergillosis (soa). an emerging pathogen, aspergillus felis, is frequently involved. the pathogenesis of urta, in particular the relationship between the infecting isolate and outcome, is poorly understood. in this study, computed tomography was used to investigate the route of fungal infection and extension in 16 cases (sna n = 7, soa n = 9) where ...201424685469
multi-resistant aspergillosis due to cryptic species.reports of cryptic species causing aspergillosis in humans are increasing in the literature. cryptic species are defined as those which are morphologically indistinguishable, although their identifications can be confirmed using molecular or other techniques which continue to become more widely available in the clinical setting. antifungal resistance has often been noted in these cases, and indeed there does appear to be a higher prevalence of reduced susceptibility in cryptic species. many of t ...201424969615
detection of aspergillus-specific antibodies by agar gel double immunodiffusion and igg elisa in feline upper respiratory tract aspergillosis.feline upper respiratory tract aspergillosis (urta) is an emerging infectious disease. the aims of this study were: (1) to assess the diagnostic value of detection of aspergillus-specific antibodies using an agar gel double immunodiffusion (agid) assay and an indirect immunoglobulin g (igg) elisa; and (2) to determine if an aspergillin derived from mycelia of aspergillus fumigatus, aspergillus niger and aspergillus flavus can be used to detect serum antibodies against cryptic aspergillus spp. in ...201525634077
antifungal activity of extracts from atacama desert fungi against paracoccidioides brasiliensis and identification of aspergillus felis as a promising source of natural bioactive compounds.fungi of the genus paracoccidioides are responsible for paracoccidioidomycosis. the occurrence of drug toxicity and relapse in this disease justify the development of new antifungal agents. compounds extracted from fungal extract have showing antifungal activity. extracts of 78 fungi isolated from rocks of the atacama desert were tested in a microdilution assay against paracoccidioides brasiliensis pb18. approximately 18% (5) of the extracts showed minimum inhibitory concentration (mic) values ≤ ...201627008375
aspergillus fumigatus-related species in clinical practice.aspergillus fumigatus is the main etiologic agent of invasive aspergillosis (ia). other aspergillus species belonging to the section fumigati (a. fumigatus complex) may occasionally be the cause of ia. these strains are often misidentified, as they cannot be distinguished from a. fumigatus by conventional morphological analysis and sequencing methods. this lack of recognition may have important consequences as these a. fumigatus-related species often display some level of intrinsic resistance to ...201627242710
interspecies discrimination of a. fumigatus and siblings a. lentulus and a. felis of the aspergillus section fumigati using the aspergenius(®) assay.the aspergenius(®) assay detects several aspergillus species and the a. fumigatus cyp51a mutations tr34/l98h/t289a/y121f that are associated with azole resistance. we evaluated its contribution in identifying a. lentulus and a. felis, 2 rare but intrinsically azole-resistant sibling species within the aspergillus section fumigati. identification of these species with conventional culture techniques is difficult and time-consuming. the assay was tested on (i) 2 a. lentulus and a. felis strains ob ...201728007314
biodiversity of species of aspergillus section fumigati in semi-desert soils in argentina.the distribution of aspergillus species in soil has been widely studied all over the world. the aim of this study was the phenotypic and genotypic characterization of species aspergillus belonging to section fumigati present in soils from two argentinian semi-desert areas having different geological conditions. altogether, 23 isolates belonging to aspergillus section fumigati were recovered and identified using a polyphasic approach including phenotypic and molecular identifications. aspergillus ...201728551307
[small animal aspergillosis and cryptococcosis in japan].canine and feline upper respiratory tract (urt) infection due to aspergillus spp. is considered an emerging disease, with the number of reported cases continuing to rise in japan. aspergillus fumigatus has been the most frequently reported etiologic agent of sino-orbital aspergillosis in dogs and cats; the other aspergillus species, aspergillus felis, aspergillus fischeri, aspergillus udagawae, aspergillus viridinutans, and a. fumigatus, have also been implicated in feline cases. the minimum inh ...201729187719
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