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ultrasonic synthetic technique to manufacture a phema nanopolymeric-based vaccine against the h6n2 avian influenza virus: a preliminary investigation.this preliminary study investigated the use of poly (2-hydroxyethyl methacrylate) (phema) nanoparticles for the delivery of the deoxyribonucleic acid (dna) vaccine pcag-hak, which expresses the full length hemagglutinin (ha) gene of the avian influenza a/eurasian coot/western australian/2727/1979 (h6n2) virus with a kozak sequence which is in the form of a pcaggs vector. the loaded and unloaded nanoparticles were characterized using field-emission scanning electron microscopy. further characteri ...201122114480
biological and genetic characterization of a low-pathogenicity avian influenza h6n2 virus originating from a healthy eurasian coot.influenza a virus, a/eurasian coot/western australia/2727/79 (h6n2), from an apparently healthy coot was characterized. this virus was able to grow on mdck cells and produce a cytopathic effect in the absence of exogenous trypsin and was further characterized as a low-pathogenicity avian influenza virus, with an intravenous pathogenicity index of 0.15 and a (321)pqaetrg(328) motif at the cleavage site of the haemagglutinin gene. it infected domestic chickens, resulting in seroconversion and inte ...201020112121
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